Santa Maria del Carmine is a church in Pisa, Italy.

The church was originally built for the Carmelite order in 1324-1328. By 1425, it was decorated with a famed, now dispersed, polyptich by Masaccio . Only one table of the altar remains in Pisa in the National Museum of San Matteo. The church itself underwent many reconstructions across the centuries. The present simple façade was designed by Alessandro Gherardesca, in the 1830s. The interior has an organ by Andrea Ravani made in 1613, and an altar with painting by Baccio Lomi, Aurelio Lomi, Santi di Tito, Alessandro Allori, Francesco Curradi, and Andrea Boscoli.

Works of Masaccio formerly at Santa Maria del Carmine

• Madonna and Child Enthroned, now in National Gallery of London.
• Crucifixion, now in Museo di Capodimonte in Naples.
• St. Paul, now in Museo Nazionale di San Matteo of Pisa.
• St. Andrew, now in Getty Museum of Los Angeles.
• St. Augustine, now in the Staatliche Museen of Berlin.
• St. Jerome, now in the Staatliche Museen of Berlin.
• Two Carmelite Saints, now in the Staatliche Museen of Berlin
• Martyrdom of St. John the Baptist and Crucifixion of St Peter, now in the Staatliche Museen of Berlin.
• Stories of St. Julian and St. Nicholas, now in the Staatliche Museen of Berlin.
• Adoration of the Magi, now in the Staatliche Museen of Berlin.